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Because AST is found in many other organs besides the liver, including the kidneys, the muscles, and the heart, having a high level of AST does not always (but often does) indicate that there is a liver problem. For example, even vigorous exercise may elevate AST levels in the body. Question About High AST Levels. Andrew T. Pavia, M.D. April 11, 2001. Question. Approximately nine months ago I had blood work done which revealed my AST levels to be over 400. An increase in AST levels may indicate liver damage or disease or muscle damage.

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Chronic liver disease and cirrhosis caused more than 39,000 deaths in the United States in 2005, according to the Centers for Disease Control and Prevention, as well as the hospitalization of about 112,000 people 1. 2019-10-23 · High or low levels of AST indicates that you are suffering from some liver disease and need medical attention. Any level other than the normal range can be a matter of concern but does not necessarily mean you have a medical problem. The results of AST may vary due to several factors such as: The ALT and AST values won’t necessarily be as high as expected for this.

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It is released into the serum when any one of these tissues is damaged.

The AST/ALT ratio is the ratio between the concentrations of the enzymes aspartate transaminase (AST) and alanine transaminase, aka alanine aminotransferase (ALT) in the blood of a human or animal.It is measured with a blood test and is sometimes useful in medical diagnosis to differentiate between causes of liver damage, or hepatotoxicity.. Most causes of liver cell injury are associated with Since AST is found in various organs like liver, kidneys, heart, skeletal muscles, and brain, elevation of AST level could also be related to acute cardiac or skeletal muscle injury. A lesser degree of ALT elevation could also signal skeletal muscle injury or it is simply a bodily reaction after vigorous exercise.
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In ealry July of this year the test was done again and as before ALT was normal but AST now came down to 51 (42 being high normal reading). Se hela listan på academic.oup.com 2018-11-29 · Both enzymes (ALT and AST) are normally present in low concentrations in serum, with values lower than 40 U/l, although the range of normality varies according to laboratories. The distribution of normality values does not show a typical distribution. Thus, values higher than the 97th percentile are considered pathological.

AST is present in both cytoplasm and mitochondria of cells. In cases involving mild tissue injury, the predominant form of AST is that from the cytoplasm. Severe tissue damage results in more of the mitochondrial enzyme being 2 dagar sedan · An AST test may be done if a child has signs of a possible liver problem, such as jaundice (yellowish skin or eyes), dark urine, nausea, vomiting, or belly pain.
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About a year later, my doctor called to say that my AST level was 93 and my ALT level was 232. This was cause for alarm so I went into the hospital. I am not a drinker but have fatty liver. CT scan, MRI, and ultrasound all looked normal but these levels remain high.

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If your results are not in the normal range, it doesn't necessarily mean that you have a medical condition needing treatment. A variety of factors that can affect your results. This serious complication can occur suddenly. There are some features that permit the differentiation of fulminant failure of WD from other causes: a high level of bilirubin that is out of proportion to the modest elevations of the transaminases, evidence of hemolysis, normal or low alkaline phosphatase, and an AST:ALT ratio greater than 4. A high AST reading may indicate that there is a liver damage however; the damage may not necessarily be caused by hepatitis C. If a test shows that there is high amount of AST but the ALT enzyme is normal, this may indicate that the cause for the increased levels of AST … Hi, Your AST and ALT levels are little higher than normal range. It is not as bad but cause of increased level need to be treated. Liver supportive medicines will also be useful.

I'm a healthy 39 y/o female with no history of hepatitis, drug/alcohol abuse.